Sculptor + CAD can be used with Sculptor Morph for free-form design modifications, and it can be used with Sculptor Morph Analysis for simulation based design. Optimized designs can be returned to CAD by using Sculptor Morph Analysis with Sculptor + Optimize and Sculptor + CAD.
Using Optimal Solutions' Arbitrary Shape Deformation (ASD) technology, you can deform shapes on the CAD geometry and import the modified geometry into your CAD system.